T1-weighted PSIR for MS Lesions in the Spinal Cord

The T1-weighted PSIR shows great potential in revealing MS lesions in the cervical spinal cord. While using this technique it is important to use the phase sensitive reconstruction to preserve the contrast between MS lesions and normal appearing tissue. Due to the nature of the reconstruction, and because T1 values of lesions can vary from patient to patient, for reliable depiction of lesions, the phase sensitive reconstruction is recommended. This is as, unlike the magnitude reconstruction, the phase sensitive reconstruction provides a contrast between different tissues that is largely independent of the chosen inversion time.